منابع مشابه
RESPIRATION AND THE AIRWAY Lung protective strategies in anaesthesia
Key points † Mechanical ventilation can have adverse effects on pulmonary function by several distinct mechanisms. † Patients undergoing one-lung ventilation or cardiopulmonary bypass are at increased risk of developing acute lung injury (ALI). † Protective ventilatory strategies may prevent or reduce ALI. † There is a lack of randomized controlled trials to guide optimal intra-operative ventil...
متن کاملPerioperative lung protective strategies
The traditional intraoperative ventilatory settings (tidal volume > 10 ml/kg ideal body weight) can be harmful even in patients with healthy lungs. In the operating theatre, safe anesthesia and optimization of oxygen delivery should be achieved while minimizing the deleterious effects of surgical trauma and avoiding iatrogenic complications. This review examines the mechanisms of perioperative ...
متن کاملProtective strategies for one-lung ventilation
provided the original work is properly cited. CC Hypoxemia and acute lung injury (ALI) are major concerns with one-lung ventilation (OLV) during thoracic surgery. Hypoxemia is usually the result of alveolar hypoventilation and an increasing shunt fraction, whereas ALI is caused by ventilatory stress (volutrauma, atelectrauma, and barotrauma), reexpansion pulmonary injury, and the lung surgery i...
متن کاملIs adalimumab protective in ischemia-reperfusion injury in lung?
Objective(s): Increasing cytokines and reactive oxygen species (ROS) during ischemia reperfusion (I-R) leads to the lung damage. Adalimumab (Ada) is a potent tumor necrosis factor-alpha (TNF-α) inhibitor agent. We aimed to evaluate whether Ada would prevent the lung tissue from damage development over the I-R process. Materials and Methods:Twenty seven Wistar albino male rats were divided into...
متن کاملPractical Anaesthesia for Lung Surgery
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2010
ISSN: 0007-0912
DOI: 10.1093/bja/aeq299